The former Senate majority leader has been a close adviser to the president-elect throughout the campaign for the White House and recently wrote a book proposing health care improvements.

The choice of Tom Daschle for secretary of health and human services poses questions about how broadly Barack Obama will apply campaign promises to limit conflicts of interest among appointees.

Arizona Gov. Janet Napolitano is President-elect Barack Obama's choice to serve as secretary of homeland security, Democratic sources said late Wednesday.

President-elect Barack Obama promised the voters change but has started his Cabinet selection process by naming several Washington insiders to top posts.

The former president has offered several concessions to help his spouse become secretary of state, including releasing the names of several major donors to his charitable foundation.

Should taxpayers in Alabama be asked to help bail out Big Three automakers whose plants are concentrated in Northern states such as Michigan and Ohio? How the auto industry pits North against South.

Rep. John Boehner of Ohio was re-elected Wednesday as House Republican leader, tasked with reviving a party diminished in numbers and fighting to stay relevant as Democrats take over the White House and strengthen their majorities in Congress.

The Arizona senator whose presidential bid was snuffed out two weeks ago by Barack Obama, was welcomed back by 2004's failed Democratic presidential nominee, John Kerry.

The son of Vice President-elect Joe Biden says he plans to fulfill his military duties and won't accept an appointment to his father's U.S. Senate seat

Mike Huckabee wouldn't rule out a 2012 run for president Wednesday, but he acknowledged it could be hard to take back the spotlight from fellow Republican Sarah Palin.

Mark Begich had every candidate's fantasy — a seemingly unbeatable opponent who became embroiled in scandal at the height of the campaign.

Despite their gains at the polls, the coalition of fiscally conservative Democrats may be put to the test by the financial crisis

An adviser to Hillary Rodham Clinton said the senator was agonizing over the decision about whether to become Barack Obama's secretary of state.

Al-Qaida's No. 2 leader used a racial epithet to insult Barack Obama in a message posted Wednesday, describing the president-elect in demeaning terms that imply he does the bidding of whites.

President-elect Barack Obama's aides have been privately talking to senators about whether Washington attorney Eric Holder would be confirmed as the next attorney general.

The Republican held a commanding place in Alaska politics while wielding power on some of the most influential committees in Congress.

The Democrats kept Sen. Joe Lieberman in the fold because politics is a game of addition and the magic number is 60:  the number of senators needed to defeat a delaying motion or filibuster.